SCHEMBL30607293

CSCC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)O)[C@@H](C)O

nearest known ligand 0.59

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	APLNR	P35414	2/20	0.59

▸	RAMP3	O60896	13/20	0.57

▸	CALCR	P30988	13/20	0.57

▸	CTSL	P07711	2/20	0.55

▸	CTSS	P25774	2/20	0.55

▸	CTSK	P43235	2/20	0.55

▸	CTSH	P09668	1/20	0.55

▸	KEAP1	Q14145	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10492942	0.90	CALCR (0.64)	CALCRKEAP1
SCHEMBL30512537	0.90	APLNR (0.56)	APLNRRAMP3CALCRCTSLCTSS
SCHEMBL29374929	0.89	APLNR (0.61)	APLNRCALCRCTSLCTSSCTSK
SCHEMBL30495696	0.89	NPY2R (0.60)	RAMP3CALCR
SCHEMBL10494174	0.88	CALCR (0.66)	APLNRRAMP3CALCR
SCHEMBL30512556	0.88	APLNR (0.62)	APLNRRAMP3CALCR
SCHEMBL30511758	0.88	CALCR (0.58)	APLNRCALCRCTSLCTSSCTSK
SCHEMBL31461953	0.87	RAMP3 (0.58)	APLNRRAMP3CALCR
SCHEMBL30883270	0.87	KEAP1 (0.61)	APLNRRAMP3CALCRKEAP1
SCHEMBL30431799	0.87	CALCR (0.64)	APLNRRAMP3CALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12383505-B2	Nanoparticle for the remodeling of cancer-associated fibroblasts	UNIVERSITY OF SOUTH CAROLINA (US)	2025-08-12	—	—	US	disclosed
US-20230310331-A1	NANOPARTICLE FOR THE REMODELING OF CANCER-ASSOCIATED FIBROBLASTS	UNIVERSITY OF SOUTH CAROLINA (US)	2023-10-05	—	—	US	disclosed