SCHEMBL30607307

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)O)C(C)C)C(C)C

nearest known ligand 0.66

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	OPRM1	P35372	7/20	0.57

▸	OPRK1	P41145	7/20	0.57

▸	MAPK8	P45983	1/20	0.56

▸	MAPK9	P45984	1/20	0.56

▸	MAPK10	P53779	1/20	0.56

▸	NPY2R	P49146	5/20	0.54

▸	NPY4R	P50391	5/20	0.54

▸	NPY5R	Q15761	5/20	0.54

▸	NPY1R	P25929	4/20	0.54

▸	TFPI	P10646	1/20	0.54

▸	OPRD1	P41143	2/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30686756	0.90	CALCR (0.56)	MAPK8MAPK9MAPK10NPY2RNPY4R
SCHEMBL30567755	0.89	NPY2R (0.59)	NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30607387	0.89	MAPK8 (0.61)	MAPK8MAPK9MAPK10NPY2RNPY4R
SCHEMBL29572169	0.88	MAPK8 (0.59)	MAPK8MAPK9MAPK10NPY2RNPY4R
SCHEMBL30262092	0.88	KDM1A (0.63)	OPRM1OPRK1NPY2RNPY4RNPY5R
SCHEMBL31276406	0.88	OPRD1 (0.62)	OPRM1OPRK1NPY2RNPY4RNPY5R
SCHEMBL31182964	0.87	MAPK8 (0.61)	MAPK8MAPK9MAPK10NPY2RNPY4R
SCHEMBL29810116	0.86	MAPK8 (0.65)	MAPK8MAPK9MAPK10NPY2RNPY4R
SCHEMBL29608298	0.86	MAPK8 (0.52)	OPRM1OPRK1MAPK8MAPK9MAPK10
SCHEMBL30864786	0.86	C5AR1 (0.59)	NPY2RNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12383505-B2	Nanoparticle for the remodeling of cancer-associated fibroblasts	UNIVERSITY OF SOUTH CAROLINA (US)	2025-08-12	—	—	US	disclosed
US-20230310331-A1	NANOPARTICLE FOR THE REMODELING OF CANCER-ASSOCIATED FIBROBLASTS	UNIVERSITY OF SOUTH CAROLINA (US)	2023-10-05	—	—	US	disclosed