Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 8/20 | 0.52 |
| ▸ | NTSR2 | O95665 | 7/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.49 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607740 | 0.94 | MAPK8 (0.54) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL31249422 | 0.91 | MAPK8 (0.55) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL29607872 | 0.90 | MAPK8 (0.59) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL31606963 | 0.89 | MAPK8 (0.48) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL29607286 | 0.89 | MAPK8 (0.66) | MAPK8MAPK9MAPK10REN | |
| SCHEMBL30689267 | 0.89 | OPRK1 (0.59) | OPRM1OPRK1NMUR2NMUR1 | |
| SCHEMBL32679555 | 0.88 | MAPK8 (0.50) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL30272472 | 0.87 | APLNR (0.57) | MAPK8MAPK9MAPK10NTSR1NTSR2 | |
| SCHEMBL31384595 | 0.86 | NPY4R (0.60) | OPRM1OPRK1 | |
| SCHEMBL31384592 | 0.86 | NPY4R (0.60) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220120732-A1 | TREATMENT OF DISEASES WITH MULTIMERIC PEPTIDES | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2022-04-21 | — | — | US | disclosed |