SCHEMBL30607457

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	5/20	0.65

▸	F2	P00734	4/20	0.65

▸	APLNR	P35414	1/20	0.63

▸	MC4R	P32245	1/20	0.62

▸	HCRTR1	O43613	1/20	0.62

▸	HCRTR2	O43614	1/20	0.62

▸	C5AR1	P21730	1/20	0.62

▸	NPY2R	P49146	6/20	0.60

▸	NPY1R	P25929	5/20	0.60

▸	NPY4R	P50391	4/20	0.60

▸	NPY5R	Q15761	4/20	0.60

▸	RAMP3	O60896	1/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30444134	0.91	APLNR (0.63)	CALCRF2APLNRHCRTR1HCRTR2
SCHEMBL31182622	0.90	CALCR (0.72)	CALCRF2NPY2RNPY1RNPY4R
SCHEMBL29707172	0.90	CALCR (0.62)	CALCRF2APLNRHCRTR1HCRTR2
SCHEMBL29783628	0.89	CALCR (0.77)	CALCRHCRTR1HCRTR2NPY2RNPY1R
SCHEMBL31183010	0.89	CALCR (0.69)	CALCRHCRTR1HCRTR2C5AR1NPY2R
SCHEMBL29767747	0.89	CALCR (0.64)	CALCRF2APLNRHCRTR1HCRTR2
SCHEMBL30932075	0.89	CALCR (0.72)	CALCRF2HCRTR1HCRTR2NPY2R
SCHEMBL30444321	0.89	APLNR (0.63)	CALCRF2APLNRHCRTR1HCRTR2
SCHEMBL31182976	0.89	CALCR (0.70)	CALCRF2APLNRNPY2RNPY1R
SCHEMBL31182498	0.89	CALCR (0.70)	CALCRF2C5AR1NPY2RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12383505-B2	Nanoparticle for the remodeling of cancer-associated fibroblasts	UNIVERSITY OF SOUTH CAROLINA (US)	2025-08-12	—	—	US	disclosed
US-20230310331-A1	NANOPARTICLE FOR THE REMODELING OF CANCER-ASSOCIATED FIBROBLASTS	UNIVERSITY OF SOUTH CAROLINA (US)	2023-10-05	—	—	US	disclosed