Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 6/20 | 0.51 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26117777 | 1.00 | GRM1 (0.58) | GRM1ALDH1A1MAPTDRD2HTR2A | |
| SCHEMBL30607601 | 0.85 | GRM1 (0.53) | GRM1ALDH1A1MAPTDRD2HTR2A | |
| SCHEMBL2076150 | 0.80 | ALDH1A1 (0.64) | ALDH1A1MAPTDRD2HTR2AKDM4E | |
| SCHEMBL30607591 | 0.80 | ALDH1A1 (0.64) | ALDH1A1MAPTDRD2HTR2AKDM4E | |
| SCHEMBL14534288 | 0.79 | TRPV1 (0.57) | HSD11B1 | |
| SCHEMBL30607698 | 0.79 | GRM1 (0.54) | GRM1ALDH1A1DRD2HTR2AKDM4E | |
| SCHEMBL2897776 | 0.78 | KDM4E (0.50) | GRM1ALDH1A1MAPTDRD2HTR2A | |
| SCHEMBL3329389 | 0.78 | KDM4E (0.50) | GRM1ALDH1A1MAPTDRD2HTR2A | |
| SCHEMBL2899849 | 0.78 | KDM4E (0.50) | GRM1ALDH1A1MAPTDRD2HTR2A | |
| SCHEMBL5482402 | 0.78 | GRM1 (0.66) | GRM1ALDH1A1MAPTKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186065-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-10-05 | — | — | WO | disclosed |