Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13999773 | 0.79 | ADRB1 (0.47) | ARHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL20139939 | 0.79 | GRM1 (0.67) | GRM1CYP2D6GSK3BDRD4DRD2 | |
| SCHEMBL26117777 | 0.79 | GRM1 (0.58) | GRM1DRD4DRD2GRM5HTR7 | |
| SCHEMBL30607641 | 0.79 | GRM1 (0.58) | GRM1DRD4DRD2GRM5HTR7 | |
| SCHEMBL3088832 | 0.77 | DRD4 (0.54) | ARDRD4DRD2GRM5HTR7 | |
| SCHEMBL2077261 | 0.76 | ADRA2C (0.56) | ARDRD4DRD2GRM5HTR7 | |
| SCHEMBL2460325 | 0.75 | GRM1 (0.45) | GRM1CYP2D6GSK3BARDRD4 | |
| SCHEMBL20140116 | 0.75 | GRM1 (0.45) | GRM1CYP2D6GSK3BARDRD4 | |
| SCHEMBL2460324 | 0.75 | GRM1 (0.45) | GRM1CYP2D6GSK3BARDRD4 | |
| Hydrochloric Acid SCHEMBL1483325 | 0.75 | ADRA2C (0.55) | ARDRD4DRD2GRM5HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186065-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-10-05 | — | — | WO | disclosed |