Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.39 |
| ▸ | AOC1 | P19801 | 5/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30607708 | 0.73 | NCOA3 (0.43) | PDE10AMAPT | |
| SCHEMBL30607539 | 0.70 | AOC1 (0.37) | AOC1AOC3LOXL2NCF1CYP2A6 | |
| SCHEMBL5971617 | 0.69 | CYP11B1 (0.40) | PDE10AMKNK1MKNK2CYP11B1CYP11B2 | |
| SCHEMBL29833912 | 0.69 | IRAK4 (0.53) | PDE10AMKNK1MKNK2MAPT | |
| SCHEMBL27845418 | 0.68 | POLB (0.52) | AOC1AOC3LOXL2ALDH1A1NCF1 | |
| SCHEMBL27845410 | 0.68 | NPC1 (0.35) | AOC1AOC3ALDH1A1NCF1SCN9A | |
| SCHEMBL27837485 | 0.67 | PDE10A (0.42) | PDE10AMKNK2ALDH1A1CYP11B2MAPT | |
| SCHEMBL27715111 | 0.66 | CA12 (0.43) | LOXL2NCF1 | |
| SCHEMBL15839178 | 0.65 | CYP17A1 (0.45) | PDE10AMKNK1MKNK2CYP11B1CYP11B2 | |
| SCHEMBL27028753 | 0.65 | MKNK2 (0.39) | PDE10AMKNK1MKNK2ALDH1A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186065-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-10-05 | — | — | WO | disclosed |