Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.37 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30607673 | 0.73 | PDE10A (0.39) | MAPTPDE10A | |
| SCHEMBL29833912 | 0.72 | IRAK4 (0.53) | KDM4EMAPTPDE10ACYP1A2 | |
| SCHEMBL30607638 | 0.70 | NCOA3 (0.42) | NCOA3HTTKDM4ECYP19A1CLK1 | |
| SCHEMBL31273773 | 0.68 | MAOA (0.47) | NCOA3HTTPDE10ACLK1CLK2 | |
| SCHEMBL29691131 | 0.67 | KDM4E (0.64) | KDM4ECYP19A1MAPTSLC2A1SLC2A2 | |
| SCHEMBL1671785 | 0.67 | KDM4E (0.46) | HTTKDM4ECYP19A1MAPTSLC2A1 | |
| SCHEMBL15839178 | 0.65 | CYP17A1 (0.45) | PDE10ACYP1A2 | |
| SCHEMBL27028753 | 0.65 | MKNK2 (0.39) | KDM4EPDE10ACYP1A2 | |
| SCHEMBL7015267 | 0.64 | HTT (0.73) | NCOA3HTTKDM4EMAPTPDE10A | |
| SCHEMBL567999 | 0.64 | CYP19A1 (0.57) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186065-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-10-05 | — | — | WO | disclosed |