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SCHEMBL30608597

SCHEMBL30608597

CC(C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H](N)CCC(N)=O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GRPR P30550 4/20 0.48
▸ CAPN1 P07384 2/20 0.48
▸ CTSB P07858 2/20 0.48
▸ MAGI3 Q5TCQ9 1/20 0.47
▸ GLP1R P43220 6/20 0.47
▸ GIPR P48546 6/20 0.47
▸ IL23R Q5VWK5 1/20 0.47
▸ DPP3 Q9NY33 2/20 0.46
▸ C5AR1 P21730 1/20 0.46
▸ TACR1 P25103 1/20 0.46
▸ CXCL8 P10145 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30608621 0.97 CAPN1 (0.50) GRPRCAPN1CTSBMAGI3GLP1R
SCHEMBL30608611 0.97 CAPN1 (0.50) GRPRCAPN1CTSBMAGI3GLP1R
SCHEMBL30608600 0.96 CAPN1 (0.51) GRPRCAPN1CTSBMAGI3GLP1R
SCHEMBL30608612 0.94 GLP1R (0.52) GRPRCAPN1CTSBGLP1RGIPR
SCHEMBL30608594 0.91 CAPN1 (0.54) GRPRCAPN1CTSBGLP1RGIPR
SCHEMBL30608581 0.90 CAPN1 (0.55) CAPN1CTSBGLP1RGIPRDPP3
SCHEMBL30608567 0.90 CAPN1 (0.60) GRPRCAPN1CTSBMAGI3GLP1R
SCHEMBL30608592 0.90 CAPN1 (0.60) GRPRCAPN1CTSBMAGI3GLP1R
SCHEMBL31057848 0.89 CAPN1 (0.59) GRPRCAPN1CTSBMAGI3GLP1R
SCHEMBL30608599 0.89 GRPR (0.55) GRPRCAPN1CTSBGLP1RGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646232-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY Université de Genève (CH) 2025-11-12 — — EP claimed
WO-2024146707-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY UNIVERSITÉ DE GENÈVE (CH) 2024-07-11 — — WO claimed
EP-4646232-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY Université de Genève (CH) 2025-11-12 — — EP disclosed
US-20250090637-A1 METHODS OF INHIBITING CEREBRAL INFLAMMATION UNIVERSITÉ DE GENÈVE (CH) 2025-03-20 — — US disclosed
CN-112469429-B Use of CCR5 inhibitors in cancer treatment 奥立安生物技术瑞士有限责任公司 2025-02-14 — — CN disclosed
CN-112469430-B Method for inhibiting cerebral inflammation 日内瓦大学 2024-12-24 — — CN disclosed
WO-2024146707-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY UNIVERSITÉ DE GENÈVE (CH) 2024-07-11 — — WO disclosed
EP-3813870-B1 CCR5 INHIBITOR FOR USE IN TREATING CANCER ORION Biotechnology Switzerland Sarl (CH) 2023-11-15 — — EP disclosed
EP-3813869-B1 CCR5 INHIBITOR FOR USE IN TREATING A NEUROINFLAMMATORY DISORDER THAT INVOLVES CEREBRAL INFLAMMATION UNIV GENEVE (CH) 2023-10-18 — — EP disclosed
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