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SCHEMBL30608612

SCHEMBL30608612

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 9/20 0.52
▸ GIPR P48546 9/20 0.52
▸ GRPR P30550 3/20 0.51
▸ CXCR4 P61073 3/20 0.50
▸ CAPN1 P07384 2/20 0.50
▸ CTSB P07858 2/20 0.50
▸ CXCL8 P10145 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30608597 0.94 GRPR (0.48) GLP1RGIPRGRPRCAPN1CTSB
SCHEMBL30608584 0.93 GLP1R (0.55) GLP1RGIPRCAPN1CTSB
SCHEMBL30608621 0.93 CAPN1 (0.50) GLP1RGIPRGRPRCXCR4CAPN1
SCHEMBL30608611 0.93 CAPN1 (0.50) GLP1RGIPRGRPRCXCR4CAPN1
SCHEMBL30608600 0.91 CAPN1 (0.51) GLP1RGIPRGRPRCXCR4CAPN1
SCHEMBL30608592 0.91 CAPN1 (0.60) GLP1RGIPRGRPRCXCR4CAPN1
SCHEMBL30608567 0.91 CAPN1 (0.60) GLP1RGIPRGRPRCXCR4CAPN1
SCHEMBL30608581 0.91 CAPN1 (0.55) GLP1RGIPRCAPN1CTSBCXCL8
SCHEMBL31057848 0.90 CAPN1 (0.59) GLP1RGIPRGRPRCAPN1CTSB
SCHEMBL30608594 0.90 CAPN1 (0.54) GLP1RGIPRGRPRCXCR4CAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646232-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY Université de Genève (CH) 2025-11-12 — — EP claimed
WO-2024146707-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY UNIVERSITÉ DE GENÈVE (CH) 2024-07-11 — — WO claimed
EP-4646232-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY Université de Genève (CH) 2025-11-12 — — EP disclosed
US-20250090637-A1 METHODS OF INHIBITING CEREBRAL INFLAMMATION UNIVERSITÉ DE GENÈVE (CH) 2025-03-20 — — US disclosed
CN-112469429-B Use of CCR5 inhibitors in cancer treatment 奥立安生物技术瑞士有限责任公司 2025-02-14 — — CN disclosed
CN-112469430-B Method for inhibiting cerebral inflammation 日内瓦大学 2024-12-24 — — CN disclosed
WO-2024146707-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY UNIVERSITÉ DE GENÈVE (CH) 2024-07-11 — — WO disclosed
EP-3813870-B1 CCR5 INHIBITOR FOR USE IN TREATING CANCER ORION Biotechnology Switzerland Sarl (CH) 2023-11-15 — — EP disclosed
EP-3813869-B1 CCR5 INHIBITOR FOR USE IN TREATING A NEUROINFLAMMATORY DISORDER THAT INVOLVES CEREBRAL INFLAMMATION UNIV GENEVE (CH) 2023-10-18 — — EP disclosed
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