Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25983052 | 0.70 | KDM4E (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18165417 | 0.69 | HEXA (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14452840 | 0.68 | KDM4E (0.59) | NPC1RAB9AMETAP2MAOAMAPT | |
| SCHEMBL16169851 | 0.68 | KDM4E (0.59) | NPC1RAB9AMETAP2MAOAMAPT | |
| SCHEMBL12151222 | 0.68 | MAOA (0.50) | NPC1RAB9AMAOAMAPTKDM4E | |
| SCHEMBL19106485 | 0.68 | HEXA (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL633763 | 0.66 | PNMT (0.68) | GABRA1GABRB2NPC1RAB9AMAOA | |
| SCHEMBL30606684 | 0.66 | PNMT (0.68) | GABRA1GABRB2NPC1RAB9AMAOA | |
| SCHEMBL2690046 | 0.66 | NPC1 (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fluorene SCHEMBL7863457 | 0.65 | MAOA (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751165-A | Preparation method of 1-azafluorene and chiral 1-azafluorene containing axis | 武汉大学深圳研究院 | 2023-09-15 | — | — | CN | disclosed |