Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | CD40 | P25942 | 2/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30609948 | 1.00 | MMP2 (0.55) | MMP2OPRD1OPRM1OPRK1MME | |
| SCHEMBL30609971 | 0.91 | CD40 (0.48) | MMP2OPRD1OPRM1OPRK1CD40 | |
| SCHEMBL30609961 | 0.91 | CD40 (0.47) | MMP2OPRD1OPRM1OPRK1CD40 | |
| SCHEMBL31138053 | 0.91 | MMP2 (0.54) | MMP2OPRD1OPRM1OPRK1CD40 | |
| SCHEMBL30609943 | 0.91 | OPRD1 (0.50) | MMP2OPRD1OPRM1OPRK1MME | |
| SCHEMBL29679713 | 0.91 | MMP2 (0.63) | MMP2OPRD1OPRM1OPRK1CHRNA1 | |
| SCHEMBL30786037 | 0.91 | MMP2 (0.63) | MMP2OPRD1OPRM1OPRK1CHRNA1 | |
| SCHEMBL31167406 | 0.91 | MMP2 (0.57) | MMP2OPRK1MME | |
| SCHEMBL31167399 | 0.91 | MMP2 (0.57) | MMP2OPRK1MME | |
| SCHEMBL29617288 | 0.89 | NPY4R (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878637-A | Cyclic hexapeptide analogue serving as mu-opioid receptor antagonist as well as preparation and application thereof | 兰州大学 | 2024-11-01 | — | — | CN | claimed |
| CN-118834271-A | Cyclic hexapeptide analogue containing aromatic structure amino acid at 3 sites and preparation and application thereof | 兰州大学 | 2024-10-25 | — | — | CN | claimed |
| CN-116970040-A | Opioid multi-target-spot cyclohexapeptide molecule with amide bond ring formation, and preparation and application thereof | 兰州大学 | 2023-10-31 | — | — | CN | claimed |
| CN-118878637-A | Cyclic hexapeptide analogue serving as mu-opioid receptor antagonist as well as preparation and application thereof | 兰州大学 | 2024-11-01 | — | — | CN | disclosed |
| CN-118878637-A | Cyclic hexapeptide analogue serving as mu-opioid receptor antagonist as well as preparation and application thereof | 兰州大学 | 2024-11-01 | — | — | CN | disclosed |
| CN-118834271-A | Cyclic hexapeptide analogue containing aromatic structure amino acid at 3 sites and preparation and application thereof | 兰州大学 | 2024-10-25 | — | — | CN | disclosed |
| CN-118834271-A | Cyclic hexapeptide analogue containing aromatic structure amino acid at 3 sites and preparation and application thereof | 兰州大学 | 2024-10-25 | — | — | CN | disclosed |
| CN-116970040-A | Opioid multi-target-spot cyclohexapeptide molecule with amide bond ring formation, and preparation and application thereof | 兰州大学 | 2023-10-31 | — | — | CN | disclosed |
| CN-116970040-A | Opioid multi-target-spot cyclohexapeptide molecule with amide bond ring formation, and preparation and application thereof | 兰州大学 | 2023-10-31 | — | — | CN | disclosed |