Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.63 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.63 |
| ▸ | HTR2A | P28223 | 11/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20774636 | 1.00 | ROCK2 (0.63) | ROCK2ROCK1HTR2AHRH4KDM4E | |
| SCHEMBL20774567 | 0.84 | HTR2A (0.68) | ROCK2ROCK1HTR2AHRH4KDM4E | |
| SCHEMBL30611366 | 0.84 | HTR2A (0.68) | ROCK2ROCK1HTR2AHRH4KDM4E | |
| SCHEMBL20774512 | 0.78 | ROCK2 (0.74) | ROCK2ROCK1POLB | |
| SCHEMBL20774897 | 0.77 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL28092365 | 0.71 | HRH4 (1.00) | HTR2AHRH4ALDH1A1PDE5APOLB | |
| SCHEMBL30611428 | 0.71 | ROCK2 (0.71) | ROCK2HTR2AHRH4KDM4EALDH1A1 | |
| SCHEMBL20774585 | 0.71 | ROCK2 (0.71) | ROCK2HTR2AHRH4KDM4EALDH1A1 | |
| SCHEMBL3642979 | 0.70 | HRH4 (0.75) | HTR2AHRH4KDM4EALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL3641724 | 0.69 | HRH4 (0.73) | HTR2AHRH4KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587112-B | Rho-related inhibitors of coiled-coil-containing protein kinases | 卡德门企业有限公司 | 2023-10-10 | — | — | CN | disclosed |