Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.59 |
| ▸ | GSK3A | P49840 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.59 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29628231 | 0.86 | SLC6A3 (0.46) | ROCK2CSF1RKDRFLT3GSK3A | |
| SCHEMBL15902337 | 0.80 | BCAT2 (0.56) | NOTUMBTKTSHRMAPTCHEK1 | |
| SCHEMBL30285287 | 0.79 | SLC6A3 (0.71) | ROCK2CSF1RKDRFLT3GSK3A | |
| SCHEMBL30841297 | 0.79 | SLC6A3 (0.66) | ROCK2CSF1RKDRFLT3GSK3A | |
| SCHEMBL9950445 | 0.76 | CDK8 (0.59) | NOTUMTSHR | |
| SCHEMBL27843639 | 0.76 | SLC6A3 (0.74) | ROCK2CSF1RKDRFLT3GSK3A | |
| SCHEMBL1775832 | 0.76 | SLC6A3 (0.74) | ROCK2CSF1RKDRFLT3GSK3A | |
| SCHEMBL29891658 | 0.75 | PTPRC (0.59) | NOTUMCHEK1PTPRC | |
| SCHEMBL69464 | 0.75 | SLC6A3 (0.67) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| SCHEMBL2159619 | 0.75 | SLC6A3 (0.60) | ROCK2CSF1RKDRFLT3GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854631-B | 4-Aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-116854631-A | 4-aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2023-10-10 | — | — | CN | disclosed |