Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30612393 | 0.88 | PTPN1 (0.43) | SMN1; SMN2PDE4BALDH1A1HTTKDM4E | |
| SCHEMBL30529592 | 0.87 | PTPN1 (0.41) | MAPTSMN1; SMN2PDE4BALDH1A1HTT | |
| SCHEMBL16794693 | 0.83 | MAPT (0.42) | IDO1GAAMAPTSMN1; SMN2UCHL1 | |
| SCHEMBL20557221 | 0.81 | MAPT (0.39) | IDO1GAAMAPTPDE4BADORA3 | |
| SCHEMBL20557551 | 0.79 | TYK2 (0.45) | IDO1GAAMAPTPDE4BADORA3 | |
| SCHEMBL20504574 | 0.78 | IDO1 (0.37) | IDO1GAAMAPTSMN1; SMN2PDE4B | |
| SCHEMBL31245703 | 0.78 | MAPT (0.40) | IDO1GAAMAPTSMN1; SMN2UCHL1 | |
| SCHEMBL24263379 | 0.77 | TYK2 (0.46) | IDO1GAAMAPTSMN1; SMN2ADORA3 | |
| SCHEMBL24263290 | 0.75 | GAA (0.37) | IDO1GAAMAPTSMN1; SMN2PDE4B | |
| SCHEMBL16794637 | 0.75 | TYK2 (0.45) | IDO1GAAMAPTADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043164-A | Imidazopyridazine or pyrazolopyrimidine compounds and compositions | 安锐生物医药科技(广州)有限公司 | 2023-11-10 | — | — | CN | disclosed |