Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 9/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 5/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 5/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29754467 | 0.89 | PDE1B (0.34) | PDE1BPDE1APDE1CKMT2A | |
| SCHEMBL31245713 | 0.84 | PDE1B (0.36) | PDE1BPDE1APDE1C | |
| SCHEMBL31245691 | 0.81 | TYK2 (0.42) | — | |
| SCHEMBL31245709 | 0.80 | TYK2 (0.53) | — | |
| SCHEMBL31245737 | 0.79 | TYK2 (0.46) | — | |
| SCHEMBL30612388 | 0.75 | TYK2 (0.41) | — | |
| SCHEMBL30452720 | 0.74 | TYK2 (0.39) | PDE1BCHRM1KMT2A | |
| SCHEMBL31245712 | 0.74 | TYK2 (0.45) | — | |
| SCHEMBL31245705 | 0.73 | TYK2 (0.47) | — | |
| SCHEMBL30612393 | 0.73 | PTPN1 (0.43) | PDE1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043164-A | Imidazopyridazine or pyrazolopyrimidine compounds and compositions | 安锐生物医药科技(广州)有限公司 | 2023-11-10 | — | — | CN | disclosed |