SCHEMBL30612759

SCHEMBL30612759

Nc1ccn([C@]2(N)O[C@H](CO)C[C@H]2O)c(=O)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3A Q14432 3/20 0.42
PDE4D Q08499 1/20 0.42
SLC29A1 Q99808 1/20 0.42
LMNA P02545 4/20 0.42
THRB P10828 1/20 0.42
MTOR P42345 1/20 0.42
MDM2 Q00987 1/20 0.42
NCOA1 Q15788 1/20 0.42
NCOA3 Q9Y6Q9 1/20 0.42
CACNA1F O60840 2/20 0.40
ALB P02768 2/20 0.40
MAPT P10636 2/20 0.40
CACNA1D Q01668 2/20 0.40
CACNA1S Q13698 2/20 0.40
CACNA1C Q13936 2/20 0.40
FGFR1 P11362 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.34
POLB P06746 2/20 0.34
ALDH1A1 P00352 1/20 0.34
NT5E P21589 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30612741 0.84 PDE3A (0.46) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL13454627 0.81 PDE3A (0.39) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL30612748 0.80 PDE3A (0.40) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL5491556 0.78 LMNA (0.52) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL30612762 0.77 PDE3A (0.36) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL5940639 0.77 PDE3A (0.44) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL30612477 0.77 LMNA (0.41) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL8104294 0.74 LMNA (0.41) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL5903747 0.73 LMNA (0.40) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL1939478 0.73 PDE3A (0.47) PDE3APDE4DSLC29A1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4504970-A1 COMPOSITIONS AND ANALYSIS OF DEPHOSPHORYLATED OLIGORIBONUCLEOTIDES New England Biolabs, Inc. (US) 2025-02-12 EP disclosed
WO-2023197015-A1 COMPOSITIONS AND ANALYSIS OF DEPHOSPHORYLATED OLIGORIBONUCLEOTIDES NEW ENGLAND BIOLABS, INC. (US) 2023-10-12 WO disclosed