SCHEMBL306128

SCHEMBL306128

CC(C)C[C@H](N)C(=O)OC(=O)[C@@H](N)CCCNC(=N)N

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 14/20 0.45
NPY1R P25929 9/20 0.45
ANPEP P15144 3/20 0.44
RNPEP Q9H4A4 2/20 0.44
DNPEP Q9ULA0 2/20 0.44
NPY5R Q15761 8/20 0.43
NPY2R P49146 5/20 0.43
SLC7A5 Q01650 1/20 0.36
DPP7 Q9UHL4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6244161 1.00 NPY4R (0.45) NPY4RNPY1RANPEPRNPEPDNPEP
SCHEMBL28712062 0.89 NPY4R (0.39) NPY4RNPY1RNPY5RNPY2RDPP7
SCHEMBL288133 0.89 NPY4R (0.39) NPY4RNPY1RNPY5RNPY2RDPP7
SCHEMBL9237239 0.89 NPY4R (0.39) NPY4RNPY1RNPY5RNPY2RDPP7
SCHEMBL1821005 0.88 NPY4R (0.40) NPY4RNPY1RANPEPRNPEPDNPEP
SCHEMBL2125107 0.88 NPY4R (0.39) NPY4RNPY1RANPEPRNPEPDNPEP
Hydrochloric Acid SCHEMBL8039440 0.88 NPY4R (0.38) NPY4RNPY1RNPY5RNPY2RDPP7
Hydrochloric Acid SCHEMBL8040222 0.88 NPY4R (0.38) NPY4RNPY1RNPY5RNPY2RDPP7
SCHEMBL15653883 0.87 NPY4R (0.41) NPY4RNPY1RANPEPRNPEPDNPEP
SCHEMBL30531669 0.87 NPY4R (0.41) NPY4RNPY1RANPEPRNPEPDNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106455664-A Composition with high content of cyclic dipeptide 三得利控股株式会社 2017-02-22 CN claimed
CN-106456633-A Sugar metabolism improving agent 三得利控股株式会社 2017-02-22 CN claimed
CN-102516382-B Antimicrobial peptide Hainanenin-5 of Amolops hainanensis, gene of antimicrobial peptide Hainanenin-5 of Amolops hainanensis, and application of gene of antimicrobial peptide Hainanenin-5 of Amolops hainanensis UNIV DALIAN TECH 2014-04-16 CN claimed
WO-2008058016-A2 ETHOID-CONTAINING COMPOUNDS, METHODS FOR PREPARING ETHOID-CONTAINING COMPOUNDS, AND METHODS FOR USE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2008-05-15 WO claimed
EP-0388226-B1 Means for the treatment of senile dementia, memory disorders and related conditions AJINOMOTO KK (JP) 1995-08-09 EP claimed
CN-113167803-B In-vitro detection method for intestinal dysbiosis of poultry 赢创运营有限公司 2024-06-07 CN disclosed
CN-117582457-A Application of bacillus coagulans BC168 in preparation of clostridium perfringens inhibiting preparation and application of bacillus coagulans BC168 in production of chicken intestinal tracts and broiler chickens 广东容大生物股份有限公司 2024-02-23 CN disclosed
EP-4313154-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF OD Therapeutics Limited (HK) 2024-02-07 EP disclosed
CN-117355337-A Protein-macromolecule conjugates and methods of use thereof 奥迪曼药业科技有限公司 2024-01-05 CN disclosed
US-20220401561-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF AJ SCIENCES (YIXING) CO., LTD (CN) 2022-12-22 US disclosed
WO-2022213201-A1 APPARATUS AND METHODOLOGIES FOR DETECTION, DIAGNOSIS, AND PROGNOSIS OF BRAIN INJURY UTI LIMITED PARTNERSHIP (CA) 2022-10-13 WO disclosed
CN-114630818-A Protein-macromolecule conjugates and methods of use thereof 北京轩义医药科技有限公司 2022-06-14 CN disclosed
WO-2004031221-A9 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-07-08 WO disclosed
WO-2004031221-A1 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-04-15 WO disclosed
EP-0979310-B1 MUTATIONS IN THE katG GENE USEFUL FOR DETECTION OF M. TUBERCULOSIS MAYO FOUNDATION (US) 2002-03-13 EP disclosed
US-5658733-A Detection of isoniazid resistant strains of M. tuberculosis MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 1997-08-19 US disclosed
EP-0021766-B1 INHIBITORS OF MAMMALIAN COLLAGENASE E.R. Squibb & Sons, Inc. (US) 1983-02-09 EP disclosed
US-4297275-A Inhibitors of mammalian collagenase E. R. SQUIBB & SONS, INC. (US) 1981-10-27 US disclosed
US-4235885-A Inhibitors of mammalian collagenase E. R. SQUIBB & SONS, INC. (US) 1980-11-25 US disclosed
US-4086136-A Process for producing a peptide using a serine or thiol proteinase (ZAIDANHOJIN) SAGAMI CHEMICAL RESEARCH CENTER (JA) 1978-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220401561-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF CD44, SSB, DNPEP NPY4R 4239/4885NPY1R 4034/4885ANPEP 39/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.