Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 12/20 | 0.39 |
| ▸ | NPY1R | P25929 | 7/20 | 0.39 |
| ▸ | NPY2R | P49146 | 5/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.36 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | OTC | P00480 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965668 | 0.91 | NPY4R (0.38) | NPY4RNPY1RNPY2RNPY5ROTC | |
| SCHEMBL7142819 | 0.90 | NPY4R (0.34) | NPY4RNPY1RNPY2RNPY5ROTC | |
| Arginine SCHEMBL904454 | 0.88 | OTC (0.41) | NPY4RNPY1RNPY2RNPY5ROTC | |
| SCHEMBL6244161 | 0.88 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RANPEP | |
| SCHEMBL306128 | 0.88 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RANPEP | |
| Leucine SCHEMBL16348676 | 0.84 | NPY4R (0.33) | NPY4RNPY1RNPY2RNPY5RSLC7A5 | |
| Arginine SCHEMBL9551434 | 0.83 | GSR (0.37) | NPY4RNPY1RNPY2RNPY5RSLC7A5 | |
| Arginine SCHEMBL6130138 | 0.83 | GSR (0.46) | NPY4RNPY1RNPY2RNPY5ROTC | |
| SCHEMBL11408461 | 0.81 | GSR (0.30) | — | |
| SCHEMBL23408857 | 0.81 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135917-A1 | Anti-Gram Negative Bacteria Agent | TOKAI UNIVERSITY (JP) | 2012-05-31 | — | — | US | disclosed |
| CN-102481369-A | Anti-gram-negative bacteria agent | UNIV TOKAI | 2012-05-30 | — | — | CN | disclosed |
| EP-2444105-A1 | ANTI-GRAM-NEGATIVE BACTERIA AGENT | Tokai University (JP) | 2012-04-25 | — | — | EP | disclosed |