Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29091607 | 1.00 | HPGD (0.56) | HPGDMAPK1RAF1CYP1A2NPSR1 | |
| SCHEMBL29091610 | 1.00 | HPGD (0.56) | HPGDMAPK1RAF1CYP1A2NPSR1 | |
| SCHEMBL29091673 | 0.83 | HPGD (0.56) | HPGDMAPK1CYP1A2NPSR1TAS1R3 | |
| SCHEMBL29689450 | 0.83 | HPGD (0.56) | HPGDMAPK1CYP1A2NPSR1TAS1R3 | |
| SCHEMBL16108226 | 0.83 | HPGD (0.56) | HPGDMAPK1CYP1A2NPSR1MMP1 | |
| SCHEMBL16108227 | 0.83 | HPGD (0.56) | HPGDMAPK1CYP1A2NPSR1MMP1 | |
| SCHEMBL29091676 | 0.83 | HPGD (0.56) | HPGDMAPK1CYP1A2NPSR1TAS1R3 | |
| SCHEMBL31067327 | 0.83 | HPGD (0.56) | HPGDMAPK1CYP1A2NPSR1TAS1R3 | |
| SCHEMBL952945 | 0.81 | MAPT (0.58) | HPGDMAPK1ALDH1A1LMNAPOLB | |
| SCHEMBL952943 | 0.81 | MAPT (0.58) | HPGDMAPK1ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925100-A | Substituted thiophenoquinolinone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-24 | — | — | CN | disclosed |