SCHEMBL952943

SCHEMBL952943

Cc1c(Cl)cccc1NC(=O)/C=N\O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.58
MAPK1 P28482 2/20 0.56
ALDH1A1 P00352 3/20 0.54
HPGD P15428 2/20 0.52
LMNA P02545 4/20 0.51
POLB P06746 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
KDM4E B2RXH2 2/20 0.50
TRPV1 Q8NER1 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL952945 1.00 MAPT (0.58) MAPTMAPK1ALDH1A1HPGDLMNA
SCHEMBL12529053 1.00 MAPT (0.58) MAPTMAPK1ALDH1A1HPGDLMNA
SCHEMBL2062661 0.84 MEN1 (0.57) MAPTMAPK1ALDH1A1HPGDLMNA
SCHEMBL2062659 0.84 MEN1 (0.57) MAPTMAPK1ALDH1A1HPGDLMNA
SCHEMBL13909387 0.84 HPGD (0.55) MAPTMAPK1ALDH1A1HPGDLMNA
SCHEMBL4189803 0.84 HPGD (0.55) MAPTMAPK1ALDH1A1HPGDLMNA
SCHEMBL2898601 0.84 HPGD (0.55) MAPTMAPK1ALDH1A1HPGDLMNA
SCHEMBL28346659 0.83 HPGD (0.58) MAPK1HPGDKDM4E
SCHEMBL11307855 0.83 HPGD (0.58) MAPK1HPGDKDM4E
SCHEMBL28004687 0.83 HPGD (0.58) MAPK1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 US disclosed
EP-1937664-B1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2011-06-15 EP disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 US disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 EP disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 MAPT 4535/4885MAPK1 4097/4885ALDH1A1 238/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT MAPT 3656/4885MAPK1 3310/4885ALDH1A1 436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.