Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | ATR | Q13535 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21463400 | 1.00 | MCHR1 (0.46) | MCHR1TNKSPDGFRBFGFR1KDR | |
| SCHEMBL21463402 | 1.00 | MCHR1 (0.46) | MCHR1TNKSPDGFRBFGFR1KDR | |
| SCHEMBL30615332 | 0.84 | TNKS (0.45) | MCHR1TNKS | |
| SCHEMBL30615602 | 0.84 | TNKS (0.45) | MCHR1TNKS | |
| SCHEMBL21464096 | 0.84 | TNKS (0.45) | MCHR1TNKS | |
| SCHEMBL21464106 | 0.84 | TNKS (0.45) | MCHR1TNKS | |
| SCHEMBL21464095 | 0.84 | TNKS (0.45) | MCHR1TNKS | |
| SCHEMBL28488291 | 0.80 | TNKS (0.48) | TNKSPIK3CA | |
| SCHEMBL28495324 | 0.79 | TNKS (0.48) | TNKSFGFR1 | |
| SCHEMBL28488276 | 0.79 | TNKS (0.48) | TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868037-B | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2023-10-13 | — | — | CN | disclosed |