Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945081 | 1.00 | MAPT (0.64) | MAPTALDH1A1MAPK1EPAS1TDP1 | |
| SCHEMBL23682559 | 0.85 | TDP1 (0.54) | MAPTALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL30615510 | 0.85 | EPAS1 (0.56) | MAPTALDH1A1MAPK1EPAS1TDP1 | |
| SCHEMBL4940492 | 0.85 | EPAS1 (0.56) | MAPTALDH1A1MAPK1EPAS1TDP1 | |
| SCHEMBL4055339 | 0.82 | MAPK1 (0.62) | MAPTALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL6565464 | 0.82 | ALDH1A1 (0.51) | MAPTALDH1A1MAPK1EPAS1TDP1 | |
| SCHEMBL11518667 | 0.82 | ALDH1A1 (0.53) | MAPTALDH1A1MAPK1EPAS1TDP1 | |
| SCHEMBL4939342 | 0.82 | EPAS1 (0.60) | MAPTALDH1A1MAPK1EPAS1TDP1 | |
| SCHEMBL4064354 | 0.82 | EPAS1 (0.59) | MAPTALDH1A1MAPK1EPAS1TDP1 | |
| SCHEMBL4943394 | 0.82 | MAPT (0.60) | MAPTALDH1A1MAPK1EPAS1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868037-B | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2023-10-13 | — | — | CN | disclosed |