Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29171502 | 0.83 | NPC1 (0.42) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL4880319 | 0.78 | NPC1 (0.39) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL396685 | 0.78 | PNMT (0.44) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL714922 | 0.69 | NPC1 (0.49) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL8604647 | 0.69 | PNMT (0.44) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL715374 | 0.68 | PNMT (0.35) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL3674040 | 0.68 | NPC1 (0.41) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL7035033 | 0.67 | PNMT (0.45) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL31303187 | 0.67 | NPC1 (0.58) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL7109699 | 0.67 | PNMT (0.41) | NPC1RAB9APNMTHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116970107-A | Catalyst combination and method for preparing poly alpha-olefin synthetic oil by using same | 万华化学集团股份有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-116903772-A | Method for preparing polyolefin plastomer | 万华化学集团股份有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-116970107-A | Catalyst combination and method for preparing poly alpha-olefin synthetic oil by using same | 万华化学集团股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116903772-A | Method for preparing polyolefin plastomer | 万华化学集团股份有限公司 | 2023-10-20 | — | — | CN | disclosed |