Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26612238 | 1.00 | ERN1 (0.36) | ERN1ALDH1A1NQO2TRPA1PPARG | |
| SCHEMBL26144370 | 0.80 | CYP1A2 (0.41) | ERN1ALDH1A1POLBTDP1KMT2A | |
| SCHEMBL4980644 | 0.80 | ERN1 (0.46) | ERN1ALDH1A1NQO2POLBTDP1 | |
| SCHEMBL18512260 | 0.78 | ALDH1A1 (0.38) | ALDH1A1NQO2TRPA1PPARGPPARD | |
| SCHEMBL30660389 | 0.78 | NNMT (0.36) | ERN1ALDH1A1POLBTDP1KMT2A | |
| SCHEMBL7971706 | 0.78 | MCHR1 (0.49) | ALDH1A1NQO2TRPA1PPARGPPARD | |
| SCHEMBL14188933 | 0.77 | TUBB1 (0.35) | ERN1ALDH1A1NQO2POLBTDP1 | |
| SCHEMBL2278549 | 0.74 | NQO1 (0.42) | ALDH1A1MITFKMT2AKDM4EHPGD | |
| SCHEMBL23971206 | 0.73 | TDP1 (0.60) | ALDH1A1POLBTDP1SMN1; SMN2KMT2A | |
| SCHEMBL30410828 | 0.73 | POLB (0.47) | ALDH1A1POLBTDP1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085701-A1 | PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| EP-4511029-A1 | PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS | Gilgamesh Pharmaceuticals, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| CN-119522098-A | Pyridine derivatives for the treatment of psychotic disorders | 吉尔伽美什制药公司 | 2025-02-25 | — | — | CN | disclosed |
| WO-2023205116-A1 | PYRIDINE DERIVATIVES FOR TREATING PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |