SCHEMBL30619658

SCHEMBL30619658

CCc1ccc(C=Nc2ccc(C)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
PTGS2 P35354 3/20 0.54
CA2 P00918 3/20 0.54
PTGS1 P23219 2/20 0.54
CA9 Q16790 2/20 0.54
CA12 O43570 1/20 0.54
CYP2C9 P11712 2/20 0.49
L3MBTL1 Q9Y468 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
KDM4E B2RXH2 3/20 0.47
MAPK1 P28482 2/20 0.47
MEN1 O00255 2/20 0.47
MAPT P10636 2/20 0.47
THRB P10828 2/20 0.47
KMT2A Q03164 2/20 0.47
TP53 P04637 1/20 0.47
ALOX15 P16050 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10013522 1.00 ALDH1A1 (0.59) ALDH1A1PTGS2CA2PTGS1CA9
SCHEMBL7775979 0.92 CYP2C9 (0.55) ALDH1A1PTGS2CA2PTGS1CA9
SCHEMBL25491825 0.87 ALDH1A1 (0.61) ALDH1A1PTGS2CA2PTGS1CA9
SCHEMBL12633723 0.86 ALDH1A1 (0.74) ALDH1A1PTGS2CA2PTGS1CA9
SCHEMBL11588746 0.86 ALDH1A1 (0.74) ALDH1A1PTGS2CA2PTGS1CA9
SCHEMBL20186922 0.86 ALDH1A1 (0.74) ALDH1A1PTGS2CA2PTGS1CA9
SCHEMBL255410 0.86 ALDH1A1 (0.74) ALDH1A1PTGS2CA2PTGS1CA9
SCHEMBL11557679 0.86 ALDH1A1 (0.74) ALDH1A1PTGS2CA2PTGS1CA9
SCHEMBL10013520 0.86 ALDH1A1 (0.56) ALDH1A1PTGS2CA2PTGS1CA9
SCHEMBL28883303 0.84 CA1 (0.53) ALDH1A1CA2CA9CA12CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861065-B Method for preparing asymmetric imine or asymmetric secondary amine compound by photocatalysis 苏州大学张家港工业技术研究院 2023-09-26 CN disclosed