Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5172404 | 0.93 | ADAMTS4 (0.55) | ADAMTS4TSHRLOXL2MTNR1AMTNR1B | |
| SCHEMBL1332798 | 0.93 | ADAMTS4 (0.55) | ADAMTS4TSHRLOXL2MTNR1AMTNR1B | |
| SCHEMBL29396939 | 0.93 | ADAMTS4 (0.55) | ADAMTS4TSHRLOXL2MTNR1AMTNR1B | |
| SCHEMBL29379275 | 0.93 | ADAMTS4 (0.55) | ADAMTS4TSHRLOXL2MTNR1AMTNR1B | |
| SCHEMBL49270 | 0.87 | LOXL2 (0.56) | ADAMTS4AKR1B1NLRP3LOXL2MTNR1A | |
| SCHEMBL31336079 | 0.87 | LOXL2 (0.56) | ADAMTS4AKR1B1NLRP3LOXL2MTNR1A | |
| SCHEMBL29365671 | 0.87 | LOXL2 (0.56) | ADAMTS4AKR1B1NLRP3LOXL2MTNR1A | |
| SCHEMBL31511816 | 0.85 | LOXL2 (0.55) | ADAMTS4AKR1B1NLRP3LOXL2MTNR1A | |
| Water SCHEMBL30025993 | 0.85 | LOXL2 (0.55) | ADAMTS4AKR1B1NLRP3LOXL2MTNR1A | |
| SCHEMBL38659080 | 0.83 | ADAMTS4 (0.49) | ADAMTS4NLRP3TSHRLOXL2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114569633-B | Intestinal selective chelators for the treatment and prevention of autism and related disorders | 轴向治疗公司 | 2023-11-17 | — | — | CN | disclosed |