SCHEMBL30620166

SCHEMBL30620166

CCCCCCOc1ccc(OB(O)O)cc1F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.49
THRB P10828 1/20 0.49
S1PR1 P21453 2/20 0.46
S1PR3 Q99500 2/20 0.46
S1PR2 O95136 1/20 0.46
LPAR2 Q9HBW0 1/20 0.46
NR5A1 Q13285 1/20 0.44
S1PR4 O95977 1/20 0.43
S1PR5 Q9H228 1/20 0.43
PLA2G2D Q9UNK4 1/20 0.41
SMPD1 P17405 3/20 0.41
FAAH O00519 6/20 0.40
CHUK O15111 1/20 0.40
DAPK3 O43293 1/20 0.40
JAK2 O60674 1/20 0.40
ROCK2 O75116 1/20 0.40
PRKCG P05129 1/20 0.40
CDK1 P06493 1/20 0.40
PIM1 P11309 1/20 0.40
RPS6KB1 P23443 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27293275 1.00 THRA (0.49) THRATHRBS1PR1S1PR3S1PR2
SCHEMBL6349214 0.83 KDM1A (0.44) TSHR
SCHEMBL6344981 0.83 L3MBTL1 (0.38) THRA
SCHEMBL10553912 0.81 SMN1; SMN2 (0.49) THRATHRBS1PR1S1PR3S1PR2
SCHEMBL7789283 0.79 THRA (0.51) THRATHRBS1PR1S1PR3S1PR2
SCHEMBL29737220 0.79 THRA (0.51) THRATHRBS1PR1S1PR3S1PR2
SCHEMBL7514162 0.79 THRA (0.51) THRATHRBS1PR1S1PR3S1PR2
SCHEMBL6657948 0.79 THRA (0.51) THRATHRBS1PR1S1PR3S1PR2
SCHEMBL8220595 0.79 THRA (0.51) THRATHRBS1PR1S1PR3S1PR2
SCHEMBL8457162 0.79 THRA (0.48) THRATHRBS1PR1S1PR3S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117165305-B Negative liquid crystal compound and preparation method and application thereof 陕西师范大学 2025-05-16 CN disclosed
CN-117165305-A Negative liquid crystal compound and preparation method and application thereof 陕西师范大学 2023-12-05 CN disclosed