Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 13/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.53 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.53 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3051748 | 0.94 | SCN9A (0.53) | STAT3SCN9ASCN7AKCNH2SCN5A | |
| SCHEMBL3062716 | 0.93 | SCN9A (0.51) | STAT3SCN9ASCN7AKCNH2SCN5A | |
| SCHEMBL3056955 | 0.90 | SCN9A (0.49) | STAT3SCN9ASCN7AKCNH2SCN5A | |
| Hydrochloric Acid SCHEMBL3047175 | 0.90 | SCN9A (0.49) | STAT3SCN9ASCN7AKCNH2SCN5A | |
| SCHEMBL3050627 | 0.89 | STAT3 (0.54) | STAT3SCN9ARAB9ANPC1TNF | |
| SCHEMBL3051080 | 0.88 | HRH3 (0.46) | STAT3SCN9ASCN7AKCNH2SCN5A | |
| Hydrochloric Acid SCHEMBL3062000 | 0.87 | STAT3 (0.57) | STAT3SCN9ARAB9A | |
| Hydrochloric Acid SCHEMBL10180648 | 0.87 | SCN9A (0.51) | STAT3SCN9ASCN7AKCNH2SCN5A | |
| SCHEMBL3059732 | 0.86 | SCN9A (0.54) | STAT3SCN9ASCN7AKCNH2SCN5A | |
| SCHEMBL3063119 | 0.86 | GAA (0.58) | STAT3RAB9ANPC1TNFNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551999-B2 | Heterocyclic compound and pharmaceutical composition thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-10-08 | — | — | US | disclosed |
| EP-2207773-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMA CO LTD (JP) | 2012-07-11 | — | — | EP | disclosed |
| US-20100261720-A1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261720-A1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | COL1A1, COL2A1, COL14A1 | STAT3 1499/4885SCN9A 2616/4885SCN7A 3238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.