Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 10/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.34 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623079 | 0.93 | TRPV1 (0.33) | LIMK2ROCK2LIMK1ROCK1BTK | |
| SCHEMBL30623097 | 0.93 | TRPV1 (0.33) | LIMK2ROCK2LIMK1ROCK1BTK | |
| SCHEMBL26645140 | 0.89 | LIMK2 (0.37) | LIMK2ROCK2LIMK1ROCK1MAPK14 | |
| SCHEMBL26645276 | 0.86 | JAK3 (0.41) | LIMK2ROCK2LIMK1ROCK1MAPK14 | |
| SCHEMBL30622386 | 0.86 | JAK3 (0.41) | LIMK2ROCK2LIMK1ROCK1MAPK14 | |
| SCHEMBL26644828 | 0.86 | JAK3 (0.41) | LIMK2ROCK2LIMK1ROCK1MAPK14 | |
| SCHEMBL30622303 | 0.86 | JAK3 (0.41) | LIMK2ROCK2LIMK1ROCK1MAPK14 | |
| SCHEMBL30622762 | 0.86 | LIMK2 (0.36) | LIMK2ROCK2LIMK1ROCK1BTK | |
| SCHEMBL30622795 | 0.85 | CSNK1E (0.42) | CDK9CCNT1SLC34A1GRIA1BTK | |
| SCHEMBL26645523 | 0.85 | CSNK1E (0.42) | CDK9CCNT1SLC34A1GRIA1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |