Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK2 | P53671 | 12/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645374 | 0.88 | LIMK2 (0.40) | LIMK2ROCK2LIMK1ROCK1JAK3 | |
| SCHEMBL30622780 | 0.86 | CDK9 (0.34) | LIMK2ROCK2LIMK1ROCK1BTK | |
| SCHEMBL30623097 | 0.84 | TRPV1 (0.33) | LIMK2ROCK2LIMK1ROCK1BTK | |
| SCHEMBL30623079 | 0.84 | TRPV1 (0.33) | LIMK2ROCK2LIMK1ROCK1BTK | |
| SCHEMBL30622787 | 0.84 | BTK (0.40) | LIMK2BTKJAK3HTR2ACCNK | |
| SCHEMBL26645177 | 0.84 | BTK (0.40) | LIMK2BTKJAK3HTR2ACCNK | |
| SCHEMBL26645802 | 0.76 | USP30 (0.39) | — | |
| SCHEMBL30622869 | 0.76 | USP30 (0.39) | — | |
| SCHEMBL30622743 | 0.76 | USP30 (0.39) | — | |
| SCHEMBL30622918 | 0.75 | CDK9 (0.39) | BTKCCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |