Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 4/20 | 0.32 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623097 | 1.00 | TRPV1 (0.33) | TRPV1NR1H2NR1H3LIMK2EIF2AK4 | |
| SCHEMBL30622780 | 0.93 | CDK9 (0.34) | LIMK2BTKROCK2LIMK1ROCK1 | |
| SCHEMBL26645585 | 0.90 | LIMK2 (0.35) | TRPV1LIMK2ROCK2LIMK1ROCK1 | |
| SCHEMBL26645012 | 0.90 | LIMK2 (0.35) | TRPV1LIMK2ROCK2LIMK1ROCK1 | |
| SCHEMBL30622951 | 0.87 | JAK3 (0.39) | TRPV1LIMK2BTKROCK2LIMK1 | |
| SCHEMBL26645744 | 0.87 | JAK3 (0.39) | TRPV1LIMK2BTKROCK2LIMK1 | |
| SCHEMBL30622762 | 0.84 | LIMK2 (0.36) | LIMK2BTKROCK2LIMK1ROCK1 | |
| SCHEMBL26645418 | 0.84 | EIF2AK4 (0.35) | TRPV1NR1H2NR1H3LIMK2EIF2AK4 | |
| SCHEMBL30622793 | 0.84 | EIF2AK4 (0.35) | TRPV1NR1H2NR1H3LIMK2EIF2AK4 | |
| SCHEMBL30622789 | 0.83 | EGFR (0.34) | TRPV1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |