Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPS1 | P31327 | 7/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | PRKG1 | Q13976 | 4/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622938 | 0.89 | RIPK3 (0.37) | GHSRUSP30MAP4K4PRKACA | |
| SCHEMBL26645141 | 0.89 | RIPK3 (0.37) | GHSRUSP30MAP4K4PRKACA | |
| SCHEMBL30622909 | 0.89 | RIPK3 (0.37) | GHSRUSP30MAP4K4PRKACA | |
| SCHEMBL26645448 | 0.89 | CPS1 (0.42) | CPS1PRKG1ROCK2PTGIRPTGDR | |
| SCHEMBL30622778 | 0.89 | NR1H2 (0.37) | GHSRUSP30GPR119 | |
| SCHEMBL30622868 | 0.87 | SRC (0.38) | BTKUSP30BRAFGPR119 | |
| SCHEMBL26645050 | 0.86 | EGFR (0.40) | CPS1PRKG1ROCK2BTK | |
| SCHEMBL30622363 | 0.86 | EGFR (0.40) | CPS1PRKG1ROCK2BTK | |
| SCHEMBL26645327 | 0.84 | CSNK1E (0.41) | CPS1JAK2JAK3PTK2BTK | |
| SCHEMBL30622834 | 0.80 | MAPK8 (0.36) | USP30GSK3BGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |