Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 6/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 6/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.36 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622927 | 1.00 | KCNK3 (0.41) | KCNK3KCNK9MAPK11MAPK14GPR119 | |
| SCHEMBL30622868 | 0.90 | SRC (0.38) | GPR119MEN1KMT2AUSP30SRC | |
| SCHEMBL30622938 | 0.87 | RIPK3 (0.37) | KCNK3KCNK9USP30 | |
| SCHEMBL26645141 | 0.87 | RIPK3 (0.37) | KCNK3KCNK9USP30 | |
| SCHEMBL30622909 | 0.87 | RIPK3 (0.37) | KCNK3KCNK9USP30 | |
| SCHEMBL26645621 | 0.86 | MAPK14 (0.40) | MAPK11MAPK14MAPK13MAPK12SRC | |
| SCHEMBL26645097 | 0.86 | MAPK14 (0.40) | MAPK11MAPK14MAPK13MAPK12SRC | |
| SCHEMBL30622834 | 0.85 | MAPK8 (0.36) | KCNK3KCNK9MAPK11MAPK14GPR119 | |
| SCHEMBL30622953 | 0.85 | KCNK3 (0.42) | KCNK3KCNK9CACNB4CACNA1ACACNA1G | |
| SCHEMBL30622883 | 0.85 | KCNK3 (0.42) | KCNK3KCNK9CACNB4CACNA1ACACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |