Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.40 |
| ▸ | SMO | Q99835 | 3/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.37 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645621 | 1.00 | MAPK14 (0.40) | MAPK14MAPK11SMOSRCKDR | |
| SCHEMBL26645239 | 0.88 | SRC (0.41) | MAPK14MAPK11SMOSRCKDR | |
| SCHEMBL30622908 | 0.86 | KCNK3 (0.41) | MAPK14MAPK11SRCKDRBRAF | |
| SCHEMBL30622927 | 0.86 | KCNK3 (0.41) | MAPK14MAPK11SRCKDRBRAF | |
| SCHEMBL26645193 | 0.85 | BCHE (0.39) | — | |
| SCHEMBL26645160 | 0.85 | BCHE (0.39) | — | |
| SCHEMBL26645433 | 0.85 | BCHE (0.39) | — | |
| SCHEMBL26645626 | 0.84 | MAPK9 (0.40) | MAPK14MAPK11SMOSRC | |
| SCHEMBL26645067 | 0.83 | SMO (0.40) | SMOSLC6A7 | |
| SCHEMBL26645225 | 0.83 | SMO (0.40) | SMOSLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |