Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 6/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 6/20 | 0.42 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.36 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.36 |
| ▸ | CACNA2D4 | Q7Z3S7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622953 | 1.00 | KCNK3 (0.42) | KCNK3KCNK9CACNB4CACNA1ACACNA1G | |
| SCHEMBL30622815 | 0.90 | CSNK1D (0.37) | KCNK3SETD7SMO | |
| SCHEMBL30622940 | 0.90 | CSNK1D (0.37) | KCNK3SETD7SMO | |
| SCHEMBL30622988 | 0.88 | NR1H2 (0.39) | SETD7SMO | |
| SCHEMBL30622801 | 0.88 | NR1H2 (0.39) | SETD7SMO | |
| SCHEMBL30622927 | 0.85 | KCNK3 (0.41) | KCNK3KCNK9CACNB4CACNA1ACACNA1G | |
| SCHEMBL30622908 | 0.85 | KCNK3 (0.41) | KCNK3KCNK9CACNB4CACNA1ACACNA1G | |
| SCHEMBL26645067 | 0.85 | SMO (0.40) | MEN1KMT2ACNR1SMO | |
| SCHEMBL26645225 | 0.85 | SMO (0.40) | MEN1KMT2ACNR1SMO | |
| SCHEMBL30622784 | 0.79 | SETD7 (0.34) | SETD7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |