Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 5/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 2/20 | 0.30 |
| ▸ | CTSS | P25774 | 2/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622923 | 1.00 | JAK3 (0.34) | JAK3BTKAAK1CA1CA2 | |
| SCHEMBL30622733 | 1.00 | JAK3 (0.34) | JAK3BTKAAK1CA1CA2 | |
| SCHEMBL26645083 | 0.88 | AAK1 (0.35) | AAK1CA1CA2CA7CA4 | |
| SCHEMBL26645166 | 0.88 | AAK1 (0.35) | AAK1CA1CA2CA7CA4 | |
| SCHEMBL26645092 | 0.88 | AAK1 (0.35) | AAK1CA1CA2CA7CA4 | |
| SCHEMBL26645234 | 0.86 | APAF1 (0.36) | — | |
| SCHEMBL26645555 | 0.86 | APAF1 (0.36) | — | |
| SCHEMBL26645232 | 0.86 | APAF1 (0.36) | — | |
| SCHEMBL30622879 | 0.85 | AAK1 (0.36) | AAK1CA1CA2CA7CA4 | |
| SCHEMBL30622865 | 0.85 | AAK1 (0.36) | AAK1CA1CA2CA7CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |