Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645555 | 1.00 | APAF1 (0.36) | APAF1LMNAPOLBMEN1KMT2A | |
| SCHEMBL26645234 | 1.00 | APAF1 (0.36) | APAF1LMNAPOLBMEN1KMT2A | |
| SCHEMBL30622923 | 0.86 | JAK3 (0.34) | — | |
| SCHEMBL30622926 | 0.86 | JAK3 (0.34) | — | |
| SCHEMBL30622733 | 0.86 | JAK3 (0.34) | — | |
| SCHEMBL26645085 | 0.81 | APAF1 (0.38) | APAF1LMNAPOLBMEN1KMT2A | |
| SCHEMBL26645145 | 0.81 | APAF1 (0.38) | APAF1LMNAPOLBMEN1KMT2A | |
| SCHEMBL26645096 | 0.81 | APAF1 (0.38) | APAF1LMNAPOLBMEN1KMT2A | |
| SCHEMBL26185732 | 0.79 | MTNR1A (0.31) | MEN1KMT2A | |
| SCHEMBL26645344 | 0.76 | ALDH1A1 (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |