Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 7/20 | 0.38 |
| ▸ | CCNC | P24863 | 2/20 | 0.36 |
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | VCP | P55072 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645691 | 1.00 | MAPK8 (0.38) | MAPK8MAPK9MAPK10EGFRCCNC | |
| SCHEMBL26645626 | 0.89 | MAPK9 (0.40) | MAPK8MAPK9MAPK10CCNCCDK8 | |
| SCHEMBL26644821 | 0.86 | BRD4 (0.37) | EGFRMAPK1BTK | |
| SCHEMBL30622334 | 0.86 | EGFR (0.33) | EGFRMAPK1BTK | |
| SCHEMBL30622384 | 0.86 | BRD4 (0.37) | EGFRMAPK1BTK | |
| SCHEMBL30622397 | 0.86 | BRD4 (0.37) | EGFRMAPK1BTK | |
| SCHEMBL26645769 | 0.86 | EGFR (0.33) | EGFRMAPK1BTK | |
| SCHEMBL30623091 | 0.85 | BTK (0.41) | EGFRMAPK1BTK | |
| SCHEMBL26645414 | 0.85 | BTK (0.41) | EGFRMAPK1BTK | |
| SCHEMBL30622347 | 0.85 | EGFR (0.35) | EGFRMAPK1KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |