Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 5/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645691 | 0.89 | MAPK8 (0.38) | MAPK9MAPK10MAPK8MAPK14CSNK1D | |
| SCHEMBL30622941 | 0.89 | MAPK8 (0.38) | MAPK9MAPK10MAPK8MAPK14CSNK1D | |
| SCHEMBL30622834 | 0.87 | MAPK8 (0.36) | MAPK9MAPK10MAPK8MAPK14CSNK1D | |
| SCHEMBL26645478 | 0.85 | GHSR (0.33) | SMOGHSR | |
| SCHEMBL26645239 | 0.84 | SRC (0.41) | MAPK14MAPK11SMOSRC | |
| SCHEMBL26645097 | 0.84 | MAPK14 (0.40) | MAPK14MAPK11SMOSRC | |
| SCHEMBL26645621 | 0.84 | MAPK14 (0.40) | MAPK14MAPK11SMOSRC | |
| SCHEMBL26645209 | 0.83 | GHSR (0.33) | MAPK14CSNK1DGHSR | |
| SCHEMBL26645143 | 0.83 | TMEM97 (0.35) | GHSR | |
| SCHEMBL26645595 | 0.78 | SMO (0.34) | SMOGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |