Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.38 |
| ▸ | AURKA | O14965 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | JAK1 | P23458 | 4/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.35 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645197 | 1.00 | MAPK14 (0.44) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL26645277 | 0.92 | BRAF (0.39) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL30622813 | 0.92 | BRAF (0.39) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL30622366 | 0.85 | MAPK14 (0.46) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL26645123 | 0.85 | MAPK14 (0.46) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL30622798 | 0.82 | CSNK1D (0.46) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL26645620 | 0.82 | CSNK1D (0.46) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL30622831 | 0.81 | MAPK14 (0.43) | MAPK14CSNK1DMAPK11EGFRGRIA1 | |
| SCHEMBL30622306 | 0.81 | MAPK14 (0.42) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL30622344 | 0.81 | MAPK14 (0.42) | MAPK14CSNK1DMAPK11AURKBAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |