Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | BRAF | P15056 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623087 | 0.89 | HTT (0.39) | GPR119SRCBRAFKDR | |
| SCHEMBL26645391 | 0.87 | MAPK14 (0.48) | MAPK14MAPK11KCNH2CSNK1A1CSNK1D | |
| SCHEMBL26645130 | 0.85 | CSNK1D (0.37) | CSNK1DCSNK1EGRIA1 | |
| SCHEMBL30622862 | 0.85 | CSNK1D (0.37) | CSNK1DCSNK1EGRIA1 | |
| SCHEMBL29308625 | 0.85 | CSNK1D (0.39) | CSNK1DCSNK1EGRIA1 | |
| SCHEMBL30622978 | 0.83 | CYP3A4 (0.39) | GPR119CSNK1A1CSNK1DEGFR | |
| SCHEMBL30622876 | 0.83 | GHSR (0.44) | GPR119CSNK1EBRAF | |
| SCHEMBL30622860 | 0.83 | GPR119 (0.40) | GPR119 | |
| SCHEMBL30622960 | 0.82 | BRD4 (0.35) | GPR119 | |
| SCHEMBL30623103 | 0.82 | MAPK14 (0.44) | MAPK14MAPK11KCNH2CSNK1A1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |