Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30982574 | 0.74 | GSK3A (0.35) | MAPTNPC1RAB9A | |
| SCHEMBL30569264 | 0.70 | CYP1A2 (0.39) | GAAMAPTKDM4ENPC1TSHR | |
| SCHEMBL10854950 | 0.70 | CYP1A2 (0.39) | GAAMAPTKDM4ENPC1TSHR | |
| SCHEMBL10583397 | 0.67 | CYP1A2 (0.42) | GAAMAPTKDM4ENPC1TSHR | |
| SCHEMBL22574714 | 0.66 | GAA (0.45) | GAAMAPTKDM4ENPC1RAB9A | |
| SCHEMBL15690127 | 0.64 | GAA (0.58) | GAAMAPTKDM4ENPC1TSHR | |
| SCHEMBL819237 | 0.63 | TSHR (0.50) | GAAMAPTKDM4ETSHRKMT2A | |
| SCHEMBL29349404 | 0.63 | CYP1A2 (0.42) | GAAMAPTKDM4ENPC1TSHR | |
| SCHEMBL9751138 | 0.63 | KDM4E (0.38) | GAAMAPTKDM4ENPC1TSHR | |
| SCHEMBL9548196 | 0.63 | KDM4E (0.72) | GAAMAPTKDM4ETSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112118891-B | Fused polycyclic pyridone compounds as inhibitors of influenza virus replication | 尼坎医疗公司 | 2023-10-31 | — | — | CN | disclosed |