Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA7 | P43166 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818173 | 0.84 | ALDH1A1 (0.53) | TSHRALDH1A1HSD17B10ESR1CYP1A2 | |
| SCHEMBL817659 | 0.81 | TSHR (0.56) | TSHRALDH1A1HSD17B10ESR1CYP1A2 | |
| SCHEMBL817678 | 0.80 | TSHR (0.43) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL817653 | 0.79 | TSHR (0.55) | TSHRALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL13969442 | 0.76 | TSHR (0.42) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL21689051 | 0.76 | KDM4E (0.43) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL12808756 | 0.76 | MEN1 (0.43) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL818444 | 0.76 | TSHR (0.39) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL24373983 | 0.73 | TSHR (0.53) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL818676 | 0.73 | LMNA (0.44) | TSHRALDH1A1HSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |