Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MDM4 | O15151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12292666 | 0.92 | MDM4 (0.50) | KMT2AMDM4TP53CASP3 | |
| SCHEMBL8226910 | 0.92 | MDM4 (0.50) | KMT2AMDM4TP53CASP3 | |
| SCHEMBL15521126 | 0.92 | MDM4 (0.54) | KMT2AMDM4TP53CASP3MDM2 | |
| SCHEMBL29352034 | 0.92 | MDM4 (0.54) | KMT2AMDM4TP53CASP3MDM2 | |
| SCHEMBL8227161 | 0.92 | MDM4 (0.54) | KMT2AMDM4TP53CASP3MDM2 | |
| SCHEMBL29362168 | 0.92 | MDM4 (0.54) | KMT2AMDM4TP53CASP3MDM2 | |
| SCHEMBL118112 | 0.92 | MDM4 (0.54) | KMT2AMDM4TP53CASP3MDM2 | |
| SCHEMBL31248559 | 0.92 | MDM4 (0.54) | KMT2AMDM4TP53CASP3MDM2 | |
| SCHEMBL8227141 | 0.90 | MDM4 (0.50) | KMT2AMDM4TP53CASP3MDM2 | |
| SCHEMBL29750165 | 0.90 | MDM4 (0.48) | KMT2AMDM4TP53CASP3MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997627-B | Cyst amide derivatives | 亥姆霍兹感染研究中心有限公司 | 2023-10-10 | — | — | CN | disclosed |