Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.66 |
| ▸ | TUBB | P07437 | 2/20 | 0.66 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.66 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.66 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.66 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.66 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.66 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.66 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.66 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.66 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.66 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.66 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.66 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.66 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28648589 | 1.00 | MAPT (0.66) | MAPTNPSR1SMN1; SMN2NPC1LMNA | |
| SCHEMBL4325550 | 0.91 | MAPT (0.77) | MAPTNPSR1SMN1; SMN2NPC1LMNA | |
| SCHEMBL14758475 | 0.88 | MAPT (0.77) | MAPTNPSR1SMN1; SMN2NPC1LMNA | |
| SCHEMBL4331808 | 0.88 | ALDH1A1 (0.65) | MAPTNPSR1SMN1; SMN2NPC1LMNA | |
| SCHEMBL4319521 | 0.88 | TUBB4A (0.67) | MAPTNPSR1SMN1; SMN2NPC1LMNA | |
| SCHEMBL4342467 | 0.86 | TUBB4A (0.70) | MAPTNPSR1SMN1; SMN2NPC1LMNA | |
| SCHEMBL28658257 | 0.85 | MEN1 (0.65) | MAPTNPSR1SMN1; SMN2NPC1LMNA | |
| SCHEMBL30628035 | 0.85 | MEN1 (0.65) | MAPTNPSR1SMN1; SMN2NPC1LMNA | |
| SCHEMBL4319491 | 0.85 | TUBB4A (0.72) | MAPTNPSR1SMN1; SMN2NPC1LMNA | |
| SCHEMBL30628030 | 0.84 | NPC1 (0.72) | MAPTNPSR1SMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620919-B | Mechanical ball milling assisted synthesis method of 2-amino-3-cyano-4H-pyran compound | 浙江工业大学 | 2023-12-12 | — | — | CN | disclosed |