Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20394114 | 1.00 | KMT2A (0.47) | KMT2AMEN1PPARGHDAC1HDAC6 | |
| SCHEMBL28134248 | 0.91 | KMT2A (0.54) | KMT2AMEN1PPARGHDAC1HDAC6 | |
| SCHEMBL30059761 | 0.91 | KMT2A (0.54) | KMT2AMEN1PPARGHDAC1HDAC6 | |
| SCHEMBL19349131 | 0.78 | MEN1 (0.61) | KMT2AMEN1MMP1MMP3ALDH1A1 | |
| SCHEMBL8615550 | 0.77 | KMT2A (0.56) | KMT2AMEN1PPARGHDAC1HDAC6 | |
| SCHEMBL30628187 | 0.77 | MMP1 (0.47) | KMT2AMEN1MMP1MMP3ALDH1A1 | |
| SCHEMBL14427596 | 0.76 | MEN1 (0.67) | KMT2AMEN1PPARGHDAC6HDAC8 | |
| SCHEMBL11164223 | 0.76 | KMT2A (0.57) | KMT2AMEN1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL15111088 | 0.75 | TRPM8 (0.56) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL7444247 | 0.74 | MEN1 (0.56) | KMT2AMEN1MMP1MMP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112156102-B | Crystal form of NUC-1031 single isomer and preparation method thereof | 济南高合医疗科技有限公司 | 2023-10-03 | — | — | CN | disclosed |