Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17420636 | 1.00 | L3MBTL1 (0.45) | L3MBTL1GLAGAAPTGS1PTGS2 | |
| SCHEMBL17420722 | 0.85 | L3MBTL1 (0.42) | L3MBTL1GLAGAAPTGS1PTGS2 | |
| SCHEMBL30628254 | 0.85 | L3MBTL1 (0.42) | L3MBTL1GLAGAAPTGS1PTGS2 | |
| SCHEMBL30628260 | 0.85 | L3MBTL1 (0.42) | L3MBTL1GLAGAAPTGS1PTGS2 | |
| SCHEMBL15647322 | 0.78 | CES1 (0.44) | ALDH1A1 | |
| SCHEMBL12385967 | 0.77 | L3MBTL1 (0.51) | L3MBTL1GLAGAAPTGS1PTGS2 | |
| SCHEMBL17420741 | 0.76 | GLA (0.53) | L3MBTL1GLAGAAALDH1A1MRGPRX4 | |
| SCHEMBL30628253 | 0.76 | GLA (0.53) | L3MBTL1GLAGAAALDH1A1MRGPRX4 | |
| SCHEMBL5007630 | 0.74 | L3MBTL1 (0.50) | L3MBTL1GLAGAAPTGS1PTGS2 | |
| SCHEMBL17420416 | 0.73 | RXRA (0.42) | L3MBTL1GLAPTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |