Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17420682 | 1.00 | TSHR (0.41) | TSHRHPGDRXRARXRBRXRG | |
| SCHEMBL30628252 | 0.86 | TSHR (0.43) | TSHRHPGDRXRARXRBRXRG | |
| SCHEMBL17420581 | 0.86 | TSHR (0.43) | TSHRHPGDRXRARXRBRXRG | |
| SCHEMBL17420416 | 0.84 | RXRA (0.42) | TSHRHPGDRXRARXRBRXRG | |
| SCHEMBL30628312 | 0.84 | RXRA (0.42) | TSHRHPGDRXRARXRBRXRG | |
| SCHEMBL17420433 | 0.81 | CNR2 (0.43) | MEN1KMT2ACYP1A2CYP2C19HTT | |
| SCHEMBL30628293 | 0.81 | CNR2 (0.43) | MEN1KMT2ACYP1A2CYP2C19HTT | |
| SCHEMBL28220174 | 0.81 | TSHR (0.44) | TSHRHPGDRXRARXRBRXRG | |
| SCHEMBL17420741 | 0.78 | GLA (0.53) | HPGDRXRARXRBRXRGCYP2C19 | |
| SCHEMBL30628253 | 0.78 | GLA (0.53) | HPGDRXRARXRBRXRGCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |