Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273755 | 1.00 | L3MBTL1 (0.45) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL68412 | 0.88 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL2309460 | 0.84 | EPHX2 (0.46) | L3MBTL1RAB9AALDH1A1MAPK1KMT2A | |
| SCHEMBL8043506 | 0.84 | CYP4F2 (0.55) | ALDH1A1CYP4Z1PPARGPPARA | |
| SCHEMBL1107143 | 0.83 | KMT2A (0.56) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL1515865 | 0.83 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL290279 | 0.83 | SLC7A5 (0.55) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL12547461 | 0.82 | ALDH1A1 (0.69) | L3MBTL1IDO1ALDH1A1MAPK1PAM | |
| SCHEMBL905142 | 0.81 | CTBP2 (0.49) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL1401401 | 0.81 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |